PB180422
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Product Introduction
Background
Sodium Pyruvate, the most common pyruvate, it is an intermediate product of glycolysis. It can directly enter and exit cells. It is a necessary nutrient for cell metabolism. In the absence of glucose, it can be used as a source of energy for cells. It is one of the commonly used additives in cell culture. Although cells can produce sodium pyruvate, some cells require additional addition of sodium pyruvate during in vitro culture. A certain amount of sodium pyruvate can also be added during clonal culture or low level of serum concentration, and sodium pyruvate also can reduce phototoxic effects caused by fluorescent substances.
Ingredient Statement
With
• 100 mM Sodium pyruvate
• Ultrapure water Dissolvent
• 1 mM Recommended working concentration
Matters Need Attention
1. This product is for research use only.
2. This product is sterilized by 0.1 μm filtration.
3. It is necessary to pay attention to the aseptic operation and avoid the contamination.
4. This product is 100 mM Sodium Pyruvate solution and dilute it to to the desired concentration before use.
Specifications
| Concentration | 100× |
| Volume | 100mL |
| Form | Liquid |
| Bacteria Detection | Negative |
| Fungi Detection | Negative |
| Mycoplasma Detection | Negative |
| Endotoxin Content | < 3 EU/mL |
| pH | 6.0-8.0 |
| Animal Origin Ingredient | Without |
| Green Features | Sustainable packaging |
| Valid Period | 12 months |
| Storage Condition | This product can be stored at 2-8℃ for 12 months. |
| Shipping Condition | Room Temperature |
Publications
Journal: Cell Death & Disease (2025) IF: 8.1
DOI: 10.1038/s41419-025-07694-x
Product Cited: MEM Non-Essential Amino Acid Solution (NEAA), 100 ×, 100 mM Sodium Pyruvate Solution, 100 ×
Journal: INTERNATIONAL IMMUNOPHARMACOLOGY (2025) IF: 4.8
DOI: 10.1016/j.intimp.2024.113982
Product Cited: 100 mM Sodium Pyruvate Solution, 100 ×, MEM Medium, Penicillin-Streptomycin Solution, 100 ×
Journal: Frontiers in Pharmacology (2025) IF: 4.4
DOI: 10.3389/fphar.2024.1503490
Product Cited: HuH-7 Cells Line, 100 mM Sodium Pyruvate Solution, 100 ×, H22 Cells Line
Journal: Nature Nanotechnology (2025) IF: 38.1
DOI: 10.1038/s41565-025-01922-3
Product Cited: β-Mercaptoethanol, 55 mM (1000 × ), 100 mM Sodium Pyruvate Solution, 100 ×, NIH/3T3 Cells Line, 1 M HEPES Solution
Journal: INTERNATIONAL JOURNAL OF HYPERTHERMIA (2025) IF: 3
DOI: 10.1080/02656736.2025.2516502
Product Cited: Hepa 1-6 Cells Line, 100 mM Sodium Pyruvate Solution, 100 ×
FAQs
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Q:1What is the purpose of sodium pyruvate in media?
AnswerSodium pyruvate serves as an additional energy source for cells in culture. It is often added to low-glucose formulations (1.0 g/L glucose) and is sometimes added to higher-glucose formulations as well. Cells can become “hooked” on sodium pyruvate however, and if it is withdrawn suddenly from the media, they may experience a short lag in growth.
