PB180120
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Product Introduction
Background
Penicillin-streptomycin solution mixture is the most commonly used antibiotic to prevent microbial contamination in vitro. Penicillin can interfere with the synthesis of bacterial cell wall, especially for Gram-positive bacteria. Streptomycin could bind to ribosomal ribosome for 30S and inhibit the synthesis of bacterial protein. It was effective for Gram-negative bacteria and Gram-positive bacteria, but especially for Gram-negative bacteria. The combined use of penicillin and streptomycin can prevent most bacterial contamination, but penicillin solution is sensitive to temperature and pH, easy to degrade at room temperature, and needs cryopreservation, the stability of penicillin solution is the most stable when pH is 6.0-6.5. Streptomycin was relatively stable, and pH 5.0-7.5 was the most stable.
Ingredient Statement
With
• 10 mM PBS (pH 6.2) Dissolvent
• 10 mg/mL Streptomycin sulfate
• 10 kU/mL Penicillin G
• Gram-positive bacteria & Gram-negative bacteria Antimicrobial spectrum
Matters Need Attention
1. This product is for research use only.
2. This product is sterilized by 0.1 μm filtration.
3. It is necessary to pay attention to the aseptic operation and avoid the pollution.
4. It is not suitable for long time storage at room temperature or 2-8℃.
5. Thaw in temperature or 37℃ and mix fully before use. Avoid repeated freezing and thawing. It is recommended to aliquot the solution and store at -5~-20℃.
6. This product is a concentrated solution and dilute it to the desired concentration before use.
Specifications
Concentration | 100× |
Volume | 125mL |
Form | Liquid |
Bacteria Detection | Negative |
Fungi Detection | Negative |
Mycoplasma Detection | Negative |
Endotoxin Content | < 3 EU/mL |
pH | 6.0-6.4 |
Animal Origin Ingredient | Without |
Green Features | Sustainable packaging |
Valid Period | 12 months |
Storage Condition | This product can be stored at -5~-20℃ for 12 months with shading light. |
Shipping Condition | Ice bag |
Publications
Journal: Frontiers in Microbiology (2025) IF: 4.0
DOI: 10.3389/fmicb.2025.1526475
Product Cited: DMEM (High glucose) Medium, RAW 264.7 Cells Line, Fetal Bovine Serum, Penicillin-Streptomycin Solution, 100 ×
Journal: JOURNAL OF DRUG TARGETING (2025) IF: 3.9
DOI: 10.1080/1061186X.2025.2526713
Product Cited: RPMI-1640 Medium, Fetal Bovine Serum, DMEM (High glucose) Medium, Penicillin-Streptomycin Solution, 100 ×, Phosphate Buffer (PBS, 1 ×)
Journal: Scientific Reports (2025) IF: 3.9
DOI: 10.1038/s41598-025-00920-8
Product Cited: HGC-27 Cells Line, AGS Cells Line, Penicillin-Streptomycin Solution, 100 ×
Journal: RSC Advances (2025) IF: 3.9
DOI: 10.1039/D4RA08710K
Product Cited: Fetal Bovine Serum, Enhanced Cell Counting Kit 8 (WST-8/CCK8), Penicillin-Streptomycin Solution, 100 ×
Journal: FOOD AND CHEMICAL TOXICOLOGY (2025) IF: 3.9
DOI: 10.1016/j.fct.2025.115574
Product Cited: EGF/Urogastrone/URG, Human, Recombinant, Donor Equine Serum, MEM Non-Essential Amino Acid Solution (NEAA), 100 ×, Penicillin-Streptomycin Solution, 100 ×, DMEM/F12 Medium, 10 mg/mL Recombinant Human Insulin Solution